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Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors
BACKGROUND: Testicular germ cell tumors (TGCTs) are characterized by an aneuploid DNA content. Aberrant expression of spindle proteins such as the Aurora kinases and the spindle checkpoint proteins MAD2 and BUB1B, are thought to contribute to the development of chromosomal instability and DNA aneupl...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856146/ https://www.ncbi.nlm.nih.gov/pubmed/20411023 http://dx.doi.org/10.4103/1477-3163.60358 |