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Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors

BACKGROUND: Testicular germ cell tumors (TGCTs) are characterized by an aneuploid DNA content. Aberrant expression of spindle proteins such as the Aurora kinases and the spindle checkpoint proteins MAD2 and BUB1B, are thought to contribute to the development of chromosomal instability and DNA aneupl...

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Detalles Bibliográficos
Autores principales: Burum-Auensen, Espen, Skotheim, Rolf I., Schjølberg, Aasa R., Røislien, Jo, Lothe, Ragnhild A., Clausen, Ole Petter F.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856146/
https://www.ncbi.nlm.nih.gov/pubmed/20411023
http://dx.doi.org/10.4103/1477-3163.60358