Interactions Between a Voltage Sensor and a Toxin via Multiscale Simulations

Gating-modifier toxins inhibit voltage-gated ion channels by binding the voltage sensors (VS) and altering the energetics of voltage-dependent gating. These toxins are thought to gain access to the VS via the membrane (i.e., by partitioning from water into the membrane before binding the VS). We use...

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Detalles Bibliográficos
Autores principales: Wee, Chze Ling, Gavaghan, David, Sansom, Mark S.P.
Formato: Texto
Lenguaje:English
Publicado: The Biophysical Society 2010
Materias:
Membrane
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856169/
https://www.ncbi.nlm.nih.gov/pubmed/20409475
http://dx.doi.org/10.1016/j.bpj.2009.12.4321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856169/
https://www.ncbi.nlm.nih.gov/pubmed/20409475
http://dx.doi.org/10.1016/j.bpj.2009.12.4321

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