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The Role of Potassium in Inflammasome Activation by Bacteria
Many Gram-negative bacteria possess a type III secretion system (TTSS(¶)) that can activate the NLRC4 inflammasome, process caspase-1 and lead to secretion of mature IL-1β. This is dependent on the presence of intracellular flagellin. Previous reports have suggested that this activation is independe...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856258/ https://www.ncbi.nlm.nih.gov/pubmed/20097760 http://dx.doi.org/10.1074/jbc.M109.067298 |