The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines

The serotonin transporter (SERT) terminates neurotransmission by removing serotonin from the synaptic cleft. In addition, it is the site of action of antidepressants (which block the transporter) and of amphetamines (which induce substrate efflux). We explored the functional importance of the N term...

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Detalles Bibliográficos
Autores principales: Sucic, Sonja, Dallinger, Stefan, Zdrazil, Barbara, Weissensteiner, René, Jørgensen, Trine N., Holy, Marion, Kudlacek, Oliver, Seidel, Stefan, Cha, Joo Hwan, Gether, Ulrik, Newman, Amy H., Ecker, Gerhard F., Freissmuth, Michael, Sitte, Harald H.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856298/
https://www.ncbi.nlm.nih.gov/pubmed/20118234
http://dx.doi.org/10.1074/jbc.M109.083154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856298/
https://www.ncbi.nlm.nih.gov/pubmed/20118234
http://dx.doi.org/10.1074/jbc.M109.083154

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