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Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure

BACKGROUND: The development of effective therapies for acute liver failure (ALF) is limited by our knowledge of the pathophysiology of this condition, and the lack of suitable large animal models of acetaminophen toxicity. Our aim was to develop a reproducible invasively-monitored porcine model of a...

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Detalles Bibliográficos
Autores principales: Newsome, Philip N, Henderson, Neil C, Nelson, Leonard J, Dabos, Costas, Filippi, Celine, Bellamy, Chris, Howie, Forbes, Clutton, Richard E, King, Tim, Lee, Alistair, Hayes, Peter C, Plevris, John N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856523/
https://www.ncbi.nlm.nih.gov/pubmed/20353598
http://dx.doi.org/10.1186/1471-230X-10-34