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Effects of clusterin over-expression on metastatic progression and therapy in breast cancer

BACKGROUND: Clusterin is a secreted glycoprotein that is upregulated in a variety of cell lines in response to stress, and enhances cell survival. A second nuclear isoform of clusterin that is associated with cell death has also been identified. The aim of this study was to determine the role(s) of...

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Detalles Bibliográficos
Autores principales: Flanagan, Louise, Whyte, Lorna, Chatterjee, Namita, Tenniswood, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856549/
https://www.ncbi.nlm.nih.gov/pubmed/20307318
http://dx.doi.org/10.1186/1471-2407-10-107