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Myostatin Is Upregulated Following Stress in an Erk-Dependent Manner and Negatively Regulates Cardiomyocyte Growth in Culture and in a Mouse Model

Myostatin is well established as a negative regulator of skeletal muscle growth, but its role in the heart is controversial. Our goal in this study was to characterize myostatin regulation following cardiomyocyte stress and to examine the role of myostatin in the regulation of cardiomyocyte size. Ne...

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Detalles Bibliográficos
Autores principales: Bish, Lawrence T., Morine, Kevin J., Sleeper, Meg M., Sweeney, H. Lee
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856679/
https://www.ncbi.nlm.nih.gov/pubmed/20419100
http://dx.doi.org/10.1371/journal.pone.0010230