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Myostatin Is Upregulated Following Stress in an Erk-Dependent Manner and Negatively Regulates Cardiomyocyte Growth in Culture and in a Mouse Model
Myostatin is well established as a negative regulator of skeletal muscle growth, but its role in the heart is controversial. Our goal in this study was to characterize myostatin regulation following cardiomyocyte stress and to examine the role of myostatin in the regulation of cardiomyocyte size. Ne...
Autores principales: | Bish, Lawrence T., Morine, Kevin J., Sleeper, Meg M., Sweeney, H. Lee |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856679/ https://www.ncbi.nlm.nih.gov/pubmed/20419100 http://dx.doi.org/10.1371/journal.pone.0010230 |
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