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Activation of the Akt Survival Pathway Contributes to TRAIL Resistance in Cancer Cells

The mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) resistance in cancer cells is not fully understood. Here, we show that the Akt survival pathway plays an important role in TRAIL resistance in human cancer cells. Specifically, we found that TRAIL treatment activates th...

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Detalles Bibliográficos
Autores principales:	Xu, Jing, Zhou, Jun-Ying, Wei, Wei-Zen, Wu, Gen Sheng
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856686/ https://www.ncbi.nlm.nih.gov/pubmed/20419107 http://dx.doi.org/10.1371/journal.pone.0010226

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