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LGN regulates mitotic spindle orientation during epithelial morphogenesis

Coordinated cell polarization and mitotic spindle orientation are thought to be important for epithelial morphogenesis. Whether spindle orientation is indeed linked to epithelial morphogenesis and how it is controlled at the molecular level is still unknown. Here, we show that the NuMA- and Gα-bindi...

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Detalles Bibliográficos
Autores principales: Zheng, Zhen, Zhu, Huabin, Wan, Qingwen, Liu, Jing, Xiao, Zhuoni, Siderovski, David P., Du, Quansheng
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856901/
https://www.ncbi.nlm.nih.gov/pubmed/20385777
http://dx.doi.org/10.1083/jcb.200910021