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A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation

Lysine acetylation of histones defines the epigenetic status of human embryonic stem cells and orchestrates DNA replication, chromosome condensation, transcription, telomeric silencing, and DNA repair. A detailed mechanistic explanation of these phenomena is impeded by the limited availability of ho...

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Detalles Bibliográficos
Autores principales: Neumann, Heinz, Hancock, Susan M., Buning, Ruth, Routh, Andrew, Chapman, Lynda, Somers, Joanna, Owen-Hughes, Tom, van Noort, John, Rhodes, Daniela, Chin, Jason W.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856916/
https://www.ncbi.nlm.nih.gov/pubmed/19818718
http://dx.doi.org/10.1016/j.molcel.2009.07.027