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A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation
Lysine acetylation of histones defines the epigenetic status of human embryonic stem cells and orchestrates DNA replication, chromosome condensation, transcription, telomeric silencing, and DNA repair. A detailed mechanistic explanation of these phenomena is impeded by the limited availability of ho...
Autores principales: | Neumann, Heinz, Hancock, Susan M., Buning, Ruth, Routh, Andrew, Chapman, Lynda, Somers, Joanna, Owen-Hughes, Tom, van Noort, John, Rhodes, Daniela, Chin, Jason W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856916/ https://www.ncbi.nlm.nih.gov/pubmed/19818718 http://dx.doi.org/10.1016/j.molcel.2009.07.027 |
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