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CtIP-BRCA1 modulates the choice of DNA double-strand break repair pathway throughout the cell cycle
The repair of DNA double-strand breaks (DSB) is tightly regulated during the cell cycle. In G1 phase, the absence of a sister chromatid means that repair of DSB occurs through non-homologous end-joining (NHEJ) or microhomology-mediated end-joining (MMEJ)1. These pathways often involve loss of DNA se...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857324/ https://www.ncbi.nlm.nih.gov/pubmed/19357644 http://dx.doi.org/10.1038/nature07955 |