Regulation of the Spontaneous Augmentation of Na(V)1.9 in Mouse Dorsal Root Ganglion Neurons: Effect of PKA and PKC Pathways

Sensory neurons in the dorsal root ganglion express two kinds of tetrodotoxin resistant (TTX-R) isoforms of voltage-gated sodium channels, Na(V)1.8 and Na(V)1.9. These isoforms play key roles in the pathophysiology of chronic pain. Of special interest is Na(V)1.9: our previous studies revealed a uni...

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Detalles Bibliográficos
Autores principales: Kakimura, Jun-ichi, Zheng, Taixing, Uryu, Noriko, Ogata, Nobukuni
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857352/
https://www.ncbi.nlm.nih.gov/pubmed/20411123
http://dx.doi.org/10.3390/md8030728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857352/
https://www.ncbi.nlm.nih.gov/pubmed/20411123
http://dx.doi.org/10.3390/md8030728

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