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Effects of Tetrodotoxin on the Mammalian Cardiovascular System
The human genome encodes nine functional voltage-gated Na(+) channels. Three of them, namely Na(v)1.5, Na(v)1.8, and Na(v)1.9, are resistant to nanomolar concentrations of tetrodotoxin (TTX; IC(50) ≥ 1 μM). The other isoforms, which are predominantly expressed in the skeletal muscle and nervous syst...
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| Formato: | Texto |
| Lenguaje: | English |
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Molecular Diversity Preservation International
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857368/ https://www.ncbi.nlm.nih.gov/pubmed/20411124 http://dx.doi.org/10.3390/md8030741 |