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Influenza virus activates inflammasomes through intracellular M2 channel

Influenza virus, a negative stranded RNA virus causing severe illness in humans and animals, stimulates the inflammasome through the NOD-like receptor (NLR), NLRP3. However, the mechanism by which influenza virus activates the NLRP3 inflammasome is unknown. Here, we show that the influenza virus M2...

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Detalles Bibliográficos
Autores principales: Ichinohe, Takeshi, Pang, Iris Kok-shuen, Iwasaki, Akiko
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857582/
https://www.ncbi.nlm.nih.gov/pubmed/20383149
http://dx.doi.org/10.1038/ni.1861