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Electro-chemical coupling in the voltage-dependent phosphatase Ci-VSP
In the voltage sensing phosphatase, Ci-VSP, a voltage sensing domain (VSD) controls a lipid phosphatase domain (PD). The mechanism by which the domains are allosterically coupled is not well understood. Using an in vivo assay, we find that the inter-domain linker that connects the VSD to the PD is e...
Autores principales: | Kohout, Susy C., Bell, Sarah C., Liu, Lijun, Xu, Qiang, Minor, Daniel L., Isacoff, Ehud Y. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857593/ https://www.ncbi.nlm.nih.gov/pubmed/20364128 http://dx.doi.org/10.1038/nchembio.349 |
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