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Murine Toll-Like Receptor 2 Activation Induces Type I Interferon Responses from Endolysosomal Compartments

BACKGROUND: Toll-like receptors (TLRs) are among the first-line sentinels for immune detection and responsiveness to pathogens. The TLR2 subfamily of TLRs (TLR1, TLR2, TLR6) form heterodimers with each other and are thus able to recognize a broad range of components from several microbes such as yea...

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Detalles Bibliográficos
Autores principales: Dietrich, Nicole, Lienenklaus, Stefan, Weiss, Siegfried, Gekara, Nelson O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857745/
https://www.ncbi.nlm.nih.gov/pubmed/20422028
http://dx.doi.org/10.1371/journal.pone.0010250