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Murine Toll-Like Receptor 2 Activation Induces Type I Interferon Responses from Endolysosomal Compartments
BACKGROUND: Toll-like receptors (TLRs) are among the first-line sentinels for immune detection and responsiveness to pathogens. The TLR2 subfamily of TLRs (TLR1, TLR2, TLR6) form heterodimers with each other and are thus able to recognize a broad range of components from several microbes such as yea...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857745/ https://www.ncbi.nlm.nih.gov/pubmed/20422028 http://dx.doi.org/10.1371/journal.pone.0010250 |