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Epitope Discovery with Phylogenetic Hidden Markov Models

Existing methods for the prediction of immunologically active T-cell epitopes are based on the amino acid sequence or structure of pathogen proteins. Additional information regarding the locations of epitopes may be acquired by considering the evolution of viruses in hosts with different immune back...

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Detalles Bibliográficos
Autores principales: Lacerda, Miguel, Scheffler, Konrad, Seoighe, Cathal
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857806/
https://www.ncbi.nlm.nih.gov/pubmed/20089717
http://dx.doi.org/10.1093/molbev/msq008