Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization

BACKGROUND: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is a crucial step when comparing measurements from these arrays. Normalization is, however, far from a solved problem. Frequ...

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Detalles Bibliográficos
Autores principales: Hulsman, Marc, Mentink, Anouk, van Someren, Eugene P, Dechering, Koen J, de Boer, Jan, Reinders, Marcel JT
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857856/
https://www.ncbi.nlm.nih.gov/pubmed/20346103
http://dx.doi.org/10.1186/1471-2105-11-156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857856/
https://www.ncbi.nlm.nih.gov/pubmed/20346103
http://dx.doi.org/10.1186/1471-2105-11-156

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