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Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
BACKGROUND: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is a crucial step when comparing measurements from these arrays. Normalization is, however, far from a solved problem. Frequ...
Autores principales: | Hulsman, Marc, Mentink, Anouk, van Someren, Eugene P, Dechering, Koen J, de Boer, Jan, Reinders, Marcel JT |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857856/ https://www.ncbi.nlm.nih.gov/pubmed/20346103 http://dx.doi.org/10.1186/1471-2105-11-156 |
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