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Pharmacological manipulation of GABA-driven activity in ovo disrupts the development of dendritic morphology but not the maturation of spinal cord network activity
BACKGROUND: In the adult nervous system, GABA acts as a major inhibitory neurotransmitter; however, at early stages of neurodevelopment, GABA receptor activation leads to membrane depolarization and accumulation of [Ca(2+)](i). The role of excitatory GABAergic neurotransmission in the development of...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857860/ https://www.ncbi.nlm.nih.gov/pubmed/20377848 http://dx.doi.org/10.1186/1749-8104-5-11 |