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Pharmacological manipulation of GABA-driven activity in ovo disrupts the development of dendritic morphology but not the maturation of spinal cord network activity

BACKGROUND: In the adult nervous system, GABA acts as a major inhibitory neurotransmitter; however, at early stages of neurodevelopment, GABA receptor activation leads to membrane depolarization and accumulation of [Ca(2+)](i). The role of excitatory GABAergic neurotransmission in the development of...

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Detalles Bibliográficos
Autores principales: Yoon, Yone J, Gokin, Alexander P, Martin-Caraballo, Miguel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857860/
https://www.ncbi.nlm.nih.gov/pubmed/20377848
http://dx.doi.org/10.1186/1749-8104-5-11