20-HETE Mediates Ozone-Induced, Neutrophil-Independent Airway Hyper-Responsiveness in Mice

BACKGROUND: Ozone, a pollutant known to induce airway hyper-responsiveness (AHR), increases morbidity and mortality in patients with obstructive airway diseases and asthma. We postulate oxidized lipids mediate in vivo ozone-induced AHR in murine airways. METHODOLOGY/PRINCIPAL FINDINGS: Male BALB/c m...

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Detalles Bibliográficos
Autores principales: Cooper, Philip R., Mesaros, A. Clementina, Zhang, Jie, Christmas, Peter, Stark, Christopher M., Douaidy, Karim, Mittelman, Michael A., Soberman, Roy J., Blair, Ian A., Panettieri, Reynold A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857875/
https://www.ncbi.nlm.nih.gov/pubmed/20422032
http://dx.doi.org/10.1371/journal.pone.0010235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857875/
https://www.ncbi.nlm.nih.gov/pubmed/20422032
http://dx.doi.org/10.1371/journal.pone.0010235

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