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Full-Length Adiponectin Attenuates Insulin Signaling and Inhibits Insulin-Stimulated Amino Acid Transport in Human Primary Trophoblast Cells

OBJECTIVE: Maternal adiponectin levels are reduced and placental nutrient transporters are upregulated in obesity and gestational diabetes mellitus; however, the effects of adiponectin on placental function are unknown. We hypothesized that adiponectin regulates placental amino acid transport. RESEA...

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Detalles Bibliográficos
Autores principales: Jones, Helen N., Jansson, Thomas, Powell, Theresa L.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857896/
https://www.ncbi.nlm.nih.gov/pubmed/20150288
http://dx.doi.org/10.2337/db09-0824