Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca(2+) Channels From Secretory Vesicles

OBJECTIVE: The aim of the study was to elucidate the cellular mechanism underlying the suppression of glucose-induced insulin secretion in mice fed a high-fat diet (HFD) for 15 weeks. RESEARCH DESIGN AND METHODS: C57BL6J mice were fed a HFD or a normal diet (ND) for 3 or 15 weeks. Plasma insulin and...

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Detalles Bibliográficos
Autores principales: Collins, Stephan C., Hoppa, Michael B., Walker, Jonathan N., Amisten, Stefan, Abdulkader, Fernando, Bengtsson, Martin, Fearnside, Jane, Ramracheya, Reshma, Toye, Ayo A., Zhang, Quan, Clark, Anne, Gauguier, Dominique, Rorsman, Patrik
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857899/
https://www.ncbi.nlm.nih.gov/pubmed/20150285
http://dx.doi.org/10.2337/db09-0791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857899/
https://www.ncbi.nlm.nih.gov/pubmed/20150285
http://dx.doi.org/10.2337/db09-0791

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