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Hedgehog Signaling in Pancreas Epithelium Regulates Embryonic Organ Formation and Adult β-Cell Function

OBJECTIVE: Current studies indicate that Hedgehog (Hh) signaling must be excluded during early stages of pancreas formation. However, conflicting evidence suggests that Hh signaling may be active later during pancreas formation and that it is required for insulin production and secretion in cultured...

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Detalles Bibliográficos
Autores principales: Lau, Janet, Hebrok, Matthias
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857901/
https://www.ncbi.nlm.nih.gov/pubmed/20185815
http://dx.doi.org/10.2337/db09-0914