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Pinpointing Synaptic Loss Caused by Alzheimer’s Disease with fMRI

During its earliest stage, before cell loss and independent of amyloid plaques and neurofibrillary tangles, Alzheimer's disease (AD) causes synaptic loss affecting the basal functional properties of neurons. In principle, synaptic loss can be detected by measuring AD-induced changes in basal fu...

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Detalles Bibliográficos
Autores principales: Brickman, Adam M., Small, Scott A., Fleisher, Adam
Formato: Texto
Lenguaje:English
Publicado: IOS Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857999/
https://www.ncbi.nlm.nih.gov/pubmed/19847048
http://dx.doi.org/10.3233/BEN-2009-0240