Distinctive Chromatin in Human Sperm Packages Genes for Embryo Development

As nucleosomes are widely replaced by protamine in mature human sperm, epigenetic contributions of sperm chromatin to embryo development have been considered highly limited. However, we find the retained nucleosomes significantly enriched at loci of developmental importance including imprinted gene...

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Detalles Bibliográficos
Autores principales: Hammoud, Saher Sue, Nix, David A., Zhang, Haiying, Purwar, Jahnvi, Carrell, Douglas T., Cairns, Bradley R.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858064/
https://www.ncbi.nlm.nih.gov/pubmed/19525931
http://dx.doi.org/10.1038/nature08162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858064/
https://www.ncbi.nlm.nih.gov/pubmed/19525931
http://dx.doi.org/10.1038/nature08162

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