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Distinctive Chromatin in Human Sperm Packages Genes for Embryo Development
As nucleosomes are widely replaced by protamine in mature human sperm, epigenetic contributions of sperm chromatin to embryo development have been considered highly limited. However, we find the retained nucleosomes significantly enriched at loci of developmental importance including imprinted gene...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858064/ https://www.ncbi.nlm.nih.gov/pubmed/19525931 http://dx.doi.org/10.1038/nature08162 |