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Promoter knock-in: a novel rational method for the fine tuning of genes

BACKGROUND: Metabolic engineering aims at channeling the metabolic fluxes towards a desired compound. An important strategy to achieve this is the modification of the expression level of specific genes. Several methods for the modification or the replacement of promoters have been proposed, but most...

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Detalles Bibliográficos
Autores principales: De Mey, Marjan, Maertens, Jo, Boogmans, Sarah, Soetaert, Wim K, Vandamme, Erick J, Cunin, Raymond, Foulquié-Moreno, Maria R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858092/
https://www.ncbi.nlm.nih.gov/pubmed/20334648
http://dx.doi.org/10.1186/1472-6750-10-26