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Promoter knock-in: a novel rational method for the fine tuning of genes
BACKGROUND: Metabolic engineering aims at channeling the metabolic fluxes towards a desired compound. An important strategy to achieve this is the modification of the expression level of specific genes. Several methods for the modification or the replacement of promoters have been proposed, but most...
Autores principales: | De Mey, Marjan, Maertens, Jo, Boogmans, Sarah, Soetaert, Wim K, Vandamme, Erick J, Cunin, Raymond, Foulquié-Moreno, Maria R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858092/ https://www.ncbi.nlm.nih.gov/pubmed/20334648 http://dx.doi.org/10.1186/1472-6750-10-26 |
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