The Coordinated P53 and Estrogen Receptor Cis-Regulation at an FLT1 Promoter SNP Is Specific to Genotoxic Stress and Estrogenic Compound

BACKGROUND: Recently, we established that a C>T single nucleotide polymorphism (SNP) in the promoter of the VEGF receptor FLT1 gene generates a ½ site p53 response element (RE-T) that results in p53 responsiveness of the promoter. The transcriptional control required an estrogen receptor (ER) ½ s...

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Detalles Bibliográficos
Autores principales: Ciribilli, Yari, Andreotti, Virginia, Menendez, Daniel, Langen, Jan-Stephan, Schoenfelder, Gilbert, Resnick, Michael A., Inga, Alberto
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858160/
https://www.ncbi.nlm.nih.gov/pubmed/20422012
http://dx.doi.org/10.1371/journal.pone.0010236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858160/
https://www.ncbi.nlm.nih.gov/pubmed/20422012
http://dx.doi.org/10.1371/journal.pone.0010236

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