Genetic variation within the HLA class III influences T1D susceptibility conferred by high risk HLA haplotypes

HLA class II DRB1 and DQB1 represent the major type 1 diabetes (T1D) genetic susceptibility loci; however, other genes in the HLA region are also involved in T1D risk. We analyzed 1411 pedigrees (2865 affected individuals) from the type 1 diabetes genetics consortium (T1DGC) genotyped for HLA classi...

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Detalles Bibliográficos
Autores principales: Valdes, Ana M, Thomson, Glenys, Barcellos, Lisa F
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858242/
https://www.ncbi.nlm.nih.gov/pubmed/20054343
http://dx.doi.org/10.1038/gene.2009.104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858242/
https://www.ncbi.nlm.nih.gov/pubmed/20054343
http://dx.doi.org/10.1038/gene.2009.104

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