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Genetic variation within the HLA class III influences T1D susceptibility conferred by high risk HLA haplotypes

HLA class II DRB1 and DQB1 represent the major type 1 diabetes (T1D) genetic susceptibility loci; however, other genes in the HLA region are also involved in T1D risk. We analyzed 1411 pedigrees (2865 affected individuals) from the type 1 diabetes genetics consortium (T1DGC) genotyped for HLA classi...

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Detalles Bibliográficos
Autores principales:	Valdes, Ana M, Thomson, Glenys, Barcellos, Lisa F
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858242/ https://www.ncbi.nlm.nih.gov/pubmed/20054343 http://dx.doi.org/10.1038/gene.2009.104

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