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Nuclear receptor Rev-erbα: a heme receptor that coordinates circadian rhythm and metabolism

Nuclear receptor Rev-erbα (NR1D1), previously considered to be an orphan nuclear receptor, is a receptor for heme, which promotes transcriptional repression via recruitment of the NCoR-HDAC3 corepressor complex. Rev-erbα gene regulation is circadian, and Rev-erbα comprises a critical negative limb o...

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Detalles Bibliográficos
Autores principales: Yin, Lei, Wu, Nan, Lazar, Mitchell A.
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858265/
https://www.ncbi.nlm.nih.gov/pubmed/20414452
http://dx.doi.org/10.1621/nrs.08001