Cargando…
Reverse genetic studies of mitochondrial DNA-based diseases using a mouse model
In the situation that it would not be able to produce model animals for mitochondrial diseases caused by mitochondrial DNA (mtDNA) with pathogenic mutations, we succeeded in generating mice with pathogenic deletion mutant mtDNA (ΔmtDNA), named “mito-mice”, by direct introduction of mitochondria with...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Japan Academy
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858368/ https://www.ncbi.nlm.nih.gov/pubmed/18941295 http://dx.doi.org/10.2183/pjab.84.155 |