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To What Extent is Blood a Reasonable Surrogate for Brain in Gene Expression Studies: Estimation from Mouse Hippocampus and Spleen

Microarrays are designed to measure genome-wide differences in gene expression. In cases where a tissue is not accessible for analysis (e.g. human brain), it is of interest to determine whether a second, accessible tissue could be used as a surrogate for transcription profiling. Surrogacy has applic...

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Detalles Bibliográficos
Autores principales: Davies, Matthew N., Lawn, Sarah, Whatley, Steven, Fernandes, Cathy, Williams, Robert W., Schalkwyk, Leonard C.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858613/
https://www.ncbi.nlm.nih.gov/pubmed/20582281
http://dx.doi.org/10.3389/neuro.15.002.2009