Chemical Genetic Inhibition of Mps1 in Stable Human Cell Lines Reveals Novel Aspects of Mps1 Function in Mitosis

BACKGROUND: Proper execution of chromosome segregation relies on tight control of attachment of chromosomes to spindle microtubules. This is monitored by the mitotic checkpoint that allows chromosome segregation only when all chromosomes are stably attached. Proper functioning of the attachment and...

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Detalles Bibliográficos
Autores principales: Sliedrecht, Tale, Zhang, Chao, Shokat, Kevan M., Kops, Geert J. P. L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858645/
https://www.ncbi.nlm.nih.gov/pubmed/20422024
http://dx.doi.org/10.1371/journal.pone.0010251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858645/
https://www.ncbi.nlm.nih.gov/pubmed/20422024
http://dx.doi.org/10.1371/journal.pone.0010251

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