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Identification and Disruption of Sperm-Specific Angiotensin Converting Enzyme-3 (ACE3) in Mouse

BACKGROUND: IZUMO1 is the only sperm protein which is proven to be essential for sperm-egg fusion. However, the IZUMO1 is a structurally simple protein with single Ig domain and seems not to include either a “fusogenic peptide” or a fusion machinery domain. This led us to assume the existence of an...

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Detalles Bibliográficos
Autores principales: Inoue, Naokazu, Kasahara, Tatsuya, Ikawa, Masahito, Okabe, Masaru
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858660/
https://www.ncbi.nlm.nih.gov/pubmed/20421979
http://dx.doi.org/10.1371/journal.pone.0010301