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In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation

SARS-coronavirus (SARS-CoV) genome expression depends on the synthesis of a set of mRNAs, which presumably are capped at their 5′ end and direct the synthesis of all viral proteins in the infected cell. Sixteen viral non-structural proteins (nsp1 to nsp16) constitute an unusually large replicase com...

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Detalles Bibliográficos
Autores principales: Bouvet, Mickaël, Debarnot, Claire, Imbert, Isabelle, Selisko, Barbara, Snijder, Eric J., Canard, Bruno, Decroly, Etienne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858705/
https://www.ncbi.nlm.nih.gov/pubmed/20421945
http://dx.doi.org/10.1371/journal.ppat.1000863