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Activation of Estrogen-Responsive Genes Does Not Require Their Nuclear Co-Localization

The spatial organization of the genome in the nucleus plays a role in the regulation of gene expression. Whether co-regulated genes are subject to coordinated repositioning to a shared nuclear space is a matter of considerable interest and debate. We investigated the nuclear organization of estrogen...

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Detalles Bibliográficos
Autores principales: Kocanova, Silvia, Kerr, Elizabeth A., Rafique, Sehrish, Boyle, Shelagh, Katz, Elad, Caze-Subra, Stephanie, Bickmore, Wendy A., Bystricky, Kerstin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858706/
https://www.ncbi.nlm.nih.gov/pubmed/20421946
http://dx.doi.org/10.1371/journal.pgen.1000922