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Activation of Estrogen-Responsive Genes Does Not Require Their Nuclear Co-Localization
The spatial organization of the genome in the nucleus plays a role in the regulation of gene expression. Whether co-regulated genes are subject to coordinated repositioning to a shared nuclear space is a matter of considerable interest and debate. We investigated the nuclear organization of estrogen...
Autores principales: | Kocanova, Silvia, Kerr, Elizabeth A., Rafique, Sehrish, Boyle, Shelagh, Katz, Elad, Caze-Subra, Stephanie, Bickmore, Wendy A., Bystricky, Kerstin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858706/ https://www.ncbi.nlm.nih.gov/pubmed/20421946 http://dx.doi.org/10.1371/journal.pgen.1000922 |
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