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Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas
BACKGROUND: Histological evidence suggests that insulin-producing beta (β)-cells arise in utero from duct-like structures of the fetal exocrine pancreas, and genetic lineage tracing studies indicate that they are maintained in the adult by self-renewal. These studies have not addressed the origin of...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858732/ https://www.ncbi.nlm.nih.gov/pubmed/20377894 http://dx.doi.org/10.1186/1471-213X-10-38 |