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Growth delay of human bladder cancer cells by Prostate Stem Cell Antigen downregulation is associated with activation of immune signaling pathways

BACKGROUND: Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI) anchored protein expressed not only in prostate but also in pancreas and bladder cancer as shown by immunohistochemistry and mRNA analysis. It has been targeted by monoclonal antibodies in preclinical animal models...

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Detalles Bibliográficos
Autores principales: Marra, Emanuele, Uva, Paolo, Viti, Valentina, Simonelli, Valeria, Dogliotti, Eugenia, De Rinaldis, Emanuele, Lahm, Armin, La Monica, Nicola, Nicosia, Alfredo, Ciliberto, Gennaro, Palombo, Fabio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858747/
https://www.ncbi.nlm.nih.gov/pubmed/20374648
http://dx.doi.org/10.1186/1471-2407-10-129