The Type I NADH Dehydrogenase of Mycobacterium tuberculosis Counters Phagosomal NOX2 Activity to Inhibit TNF-α-Mediated Host Cell Apoptosis

The capacity of infected cells to undergo apoptosis upon insult with a pathogen is an ancient innate immune defense mechanism. Consequently, the ability of persisting, intracellular pathogens such as the human pathogen Mycobacterium tuberculosis (Mtb) to inhibit infection-induced apoptosis of macrop...

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Detalles Bibliográficos
Autores principales: Miller, Jessica L., Velmurugan, Kamalakannan, Cowan, Mark J., Briken, Volker
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858756/
https://www.ncbi.nlm.nih.gov/pubmed/20421951
http://dx.doi.org/10.1371/journal.ppat.1000864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858756/
https://www.ncbi.nlm.nih.gov/pubmed/20421951
http://dx.doi.org/10.1371/journal.ppat.1000864

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