P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons

Glycogen synthase kinase-3 (GSK3) is a key player in the regulation of neuronal survival. Herein, we report evidence of an interaction between P2X7 receptors with NMDA and BDNF receptors at the level of GSK3 signalling and neuroprotection. The activation of these receptors in granule neurons led to...

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Detalles Bibliográficos
Autores principales: Ortega, Felipe, Pérez-Sen, Raquel, Morente, Verónica, Delicado, Esmerilda G., Miras-Portugal, Maria Teresa
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858808/
https://www.ncbi.nlm.nih.gov/pubmed/20146080
http://dx.doi.org/10.1007/s00018-010-0278-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858808/
https://www.ncbi.nlm.nih.gov/pubmed/20146080
http://dx.doi.org/10.1007/s00018-010-0278-x

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