Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

Genetically encoded calcium indicators (GECIs) can be used to image activity in defined neuronal populations. However, current GECIs produce inferior signals compared to synthetic indicators and recording electrodes, precluding detection of low firing rates. We developed a single-wavelength GECI bas...

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Detalles Bibliográficos
Autores principales: Tian, Lin, Hires, S. Andrew, Mao, Tianyi, Huber, Daniel, Chiappe, M. Eugenia, Chalasani, Sreekanth H., Petreanu, Leopoldo, Akerboom, Jasper, McKinney, Sean A., Schreiter, Eric R., Bargmann, Cornelia I., Jayaraman, Vivek, Svoboda, Karel, Looger, Loren L.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858873/
https://www.ncbi.nlm.nih.gov/pubmed/19898485
http://dx.doi.org/10.1038/nmeth.1398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858873/
https://www.ncbi.nlm.nih.gov/pubmed/19898485
http://dx.doi.org/10.1038/nmeth.1398

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