Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced γH2A.X Foci

Nonsynonymous SNPs (nsSNPs) in DNA repair genes may be important determinants of DNA damage and cancer risk. We applied a set of screening criteria to a large number of nsSNPs and selected a subset of SNPs that were likely candidates for phenotypic effects on DNA double-strand break repair (DSBR). I...

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Detalles Bibliográficos
Autores principales: Markunas, Christina A., Umbach, David M., Xu, Zongli, Taylor, Jack A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858903/
https://www.ncbi.nlm.nih.gov/pubmed/20445776
http://dx.doi.org/10.1155/2008/387423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858903/
https://www.ncbi.nlm.nih.gov/pubmed/20445776
http://dx.doi.org/10.1155/2008/387423

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