Genetic and Epigenetic Tumor Suppressor Gene Silencing Are Distinct Molecular Phenotypes Driven by Growth Promoting Mutations in Nonsmall Cell Lung Cancer

Both genetic and epigenetic alterations characterize human nonsmall cell lung cancer (NSCLC), but the biological processes that create or select these alterations remain incompletely investigated. Our hypothesis posits that a roughly reciprocal relationship between the propensity for promoter hyperm...

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Detalles Bibliográficos
Autores principales: Marsit, Carmen J., Houseman, E. Andres, Nelson, Heather H., Kelsey, Karl T.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858933/
https://www.ncbi.nlm.nih.gov/pubmed/20445774
http://dx.doi.org/10.1155/2008/215809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858933/
https://www.ncbi.nlm.nih.gov/pubmed/20445774
http://dx.doi.org/10.1155/2008/215809

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