Age-Dependent Cancer Risk Is Not Different in between MSH2 and MLH1 Mutation Carriers

Lynch syndrome is mostly characterized by early-onset colorectal and endometrial adenocarcinomas. Over 90% of the causal mutations occur in two mismatch repair genes, MSH2 and MLH1. The aim of this study was to evaluate the age-dependent cancer risk in MSH2 or MLH1 mutation carriers from data of DNA...

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Detalles Bibliográficos
Autores principales: Olschwang, Sylviane, Yu, Kai, Lasset, Christine, Baert-Desurmont, Stéphanie, Buisine, Marie-Pierre, Wang, Qing, Hutter, Pierre, Rouleau, Etienne, Caron, Olivier, Bourdon, Violaine, Thomas, Gilles
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859022/
https://www.ncbi.nlm.nih.gov/pubmed/20445804
http://dx.doi.org/10.1155/2009/791754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859022/
https://www.ncbi.nlm.nih.gov/pubmed/20445804
http://dx.doi.org/10.1155/2009/791754

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